Analysis of Sterilization Process for Cosmetic Packaging


Aiming at the defects in the sterilization and disinfec […]

Aiming at the defects in the sterilization and disinfection of cosmetic packaging bottles in the cosmetics industry in my country for many years, the old technology has been used for reference, the international advanced disinfection industry is referenced, and the "GMP Verification Guidelines" and "disinfection technical specifications" requirements formulated by the Ministry of Health are designed and manufactured. "JZCF-B" series packaging container ozone disinfection system, the disinfection effect is obvious. Cosmetic packaging containers require advanced sterilization process analysis;
The principle of ozone sterilization
The sterilization of ozone belongs to the biochemical oxidation reaction. Ozone oxidation decomposes the enzymes necessary for the oxidation of glucose in bacteria; it can also directly interact with bacteria and viruses, destroy their cell walls and ribonucleic acid, decompose DNA, RNA, proteins, lipids and polysaccharides and other macromolecular polymers to make bacteria The material metabolism, growth and reproduction process of the cell is destroyed; it can also penetrate the cell membrane tissue, invade the cell membrane and act on the outer membrane lipoprotein and internal lipopolysaccharide, causing the cell to undergo permeability aberration, leading to the cell's lysis and death, and will die The genetic genes, parasitic strains, parasitic virus particles, bacteriophages, mycoplasma and pyrogens (bacterial virus metabolites, endotoxins) in the bacteria are dissolved, denatured and died. Looking at the principle of aseptic technology on microorganisms, it can be divided into three types: bacteriostasis, sterilization and bacteriolysis. The application of ozone as a sterilizing agent belongs to bacteriolysis.
In the "Disinfection Technical Specifications" promulgated by the Ministry of Health in 1991, the principle of ozone sterilization is also introduced:
"Scientific research shows that ozone has a strong bactericidal effect." "The molecular structure of ozone is unstable at room temperature and pressure, and it quickly decomposes into oxygen (O2) and a single oxygen atom (O). The latter has a strong Active, has a strong oxidizing effect on bacteria. Ozone oxidation decomposes the enzymes necessary for the oxidation of glucose inside the bacteria, thereby destroying the cell membrane and killing it, and the excess oxygen atoms will recombine themselves into ordinary oxygen molecules (O2). There are no toxic residues, so it is called “non-pollution disinfectant.” It not only has a strong ability to kill various bacteria (including hepatitis virus, Escherichia coli, Pseudomonas aeruginosa and other bacteria), but also kills Mold is also very effective."